Hematological Changes Among Patients With Dengue Fever

Abstract

Background: Dengue fever is a painful febrile illness caused by a mosquito-borne Arbovirus. Epidemic episodes occur especially during rainy season.  All ages and both sexes are susceptible to dengue fever. It is widely prevalent in our country. All four serotypes have been reported. Complete Blood count (CBC) is an important part of in the diagnosis patients with dengue fever and the serological tests is necessary to confirmed it.

Aim: To evaluate the hematological parameters in the patients with dengue fever and correlate those changes with serological tests.

Results: This study include 95 patients with dengue fever from Beit al-Faqih district, Hodeidah Governorate, 50(52.6%) were males and 45(47.4%) were females. Out of 95 patients 44 (46.3%) have both IgM and IgG antibodies against Dengue virus, 30(31.6%) have antibodies IgG only while 21(22.1%) have IgM antibodies only. Leukopenia and Thrombocytopenia was the most common hematological findings in the patients especially those who had positivity for both IgG and IgM antibodies.

Conclusion: Hematology profiles such as white blood cells, platelets play important role in the early diagnosis and predicting prognosis of patients with dengue fever, there was a significant association between thrombocytopenia and serological markers.